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Cheesy Chicken Broccoli Alfredo Casserole

Cheesy Chicken Broccoli Alfredo Casserole for Cozy Nights

This Cheesy Chicken Broccoli Alfredo Casserole is a one-pan comfort meal that brings the family together with creamy pasta, tender chicken, and vibrant broccoli.
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Prep Time 5 minutes
Cook Time 50 minutes
Resting Time 10 minutes
Total Time 1 hour 5 minutes
Servings: 6 servings
Course: Dinner
Cuisine: American
Calories: 420
Ingredients Equipment Method Nutrition Notes

Ingredients
  

For the Casserole
  • 1 cup Alfredo Sauce store-bought or homemade
  • 1 cup Chicken Broth vegetable broth can be substituted
  • 1 tablespoon Italian Seasoning dried herbs if fresh is unavailable
  • 1 teaspoon Garlic Powder or fresh garlic, adjusted to taste
  • 1 teaspoon Kosher Salt adjust based on saltiness of Alfredo sauce
  • 1 teaspoon Onion Powder or sautéed fresh onions
  • 1 teaspoon Black Pepper freshly cracked for best flavor
  • 1 teaspoon Crushed Red Pepper optional for spice
  • 12 ounces Penne Pasta uncooked; substitute with any pasta shape
  • 2 cups Cooked Shredded Chicken can use rotisserie chicken
  • 2 cups Chopped Fresh Broccoli or thawed frozen broccoli
  • 2 cups Mozzarella Cheese can mix with Italian cheese blend
  • 1 cup Parmesan Cheese Pecorino Romano can be used instead

Equipment

  • 9x13-inch Baking Dish

Method
 

Step-by-Step Instructions
  1. Preheat your oven to 425°F (220°C) and lightly grease a 9x13-inch baking dish with cooking spray.
  2. In the greased baking dish, combine the Alfredo sauce, chicken broth, Italian seasoning, garlic powder, kosher salt, onion powder, black pepper, and crushed red pepper. Stir until smooth.
  3. Add the uncooked penne pasta, shredded chicken, and chopped broccoli to the sauce mixture. Mix gently until everything is well-coated.
  4. Add the mozzarella and Parmesan cheeses to the mixture, folding them in until evenly distributed.
  5. Cover the casserole with aluminum foil and bake for 40 minutes, stirring halfway through.
  6. Remove the foil, stir gently, and sprinkle the remaining mozzarella cheese on top. Bake uncovered for an additional 10-15 minutes.
  7. Allow the casserole to rest for 10 minutes before serving warm.

Nutrition

Serving: 1servingCalories: 420kcalCarbohydrates: 45gProtein: 30gFat: 18gSaturated Fat: 10gMonounsaturated Fat: 2gCholesterol: 90mgSodium: 850mgPotassium: 600mgFiber: 3gSugar: 2gVitamin A: 800IUVitamin C: 30mgCalcium: 350mgIron: 2mg

Notes

Season wisely based on the flavor of your Alfredo sauce and adjust baking time if using cold ingredients.

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